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MAP2K7 抗体 (pThr275)

This 兔 多克隆 antibody specifically detects MAP2K7 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1532061
发货至: 中国
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Quick Overview for MAP2K7 抗体 (pThr275) (ABIN1532061)

抗原

See all MAP2K7 抗体
MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

适用

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人, 小鼠, 大鼠

宿主

  • 140
  • 5
兔

克隆类型

  • 121
  • 24
多克隆

标记

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This MAP2K7 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 40
    • 26
    • 24
    • 8
    • 5
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    • 2
    • 2
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    • 2
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    • 1
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    AA 241-290, pThr275

    原理

    MEK-7 (phospho Thr275) Antibody

    特异性

    Phospho-MEK-7 (T275) Polyclonal Antibody detects endogenous levels of MEK-7 protein only when phosphorylated at T275.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MAP2K7 around the phosphorylation site of Thr275. AA range:241-290

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

    别名

    MAP2K7

    背景

    Synonyms: MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4, Dual specificity mitogen-activated protein kinase kinase 7, MAP kinase kinase 7, MAPKK 7, JNK-activating kinase 2, MAPK/ERK kinase 7, MEK 7, Stress-activated protein kinase kinase 4, SAPK kinase 4, S

    Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

    Gene Name: MAP2K7

    Protein Name: Dual specificity mitogen-activated protein kinase kinase 7

    分子量

    47 kDa

    基因ID

    5609

    OMIM

    603014

    UniProt

    O14733

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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