我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

RELB 抗体 (pSer552)

The 兔多克隆 anti-RELB antibody is suitable to detect RELB in samples from 人和小鼠. It has been validated for WB, IHC, ELISA 和 IF.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using RelB (Phospho-Ser552) Antibody. (RELB 抗体 (pSer552))

IHC

2 images

产品编号 ABIN1531964

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RELB 抗体 (pSer552) (ABIN1531964)

抗原

See all RELB 抗体

RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This RELB antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Discover our top product RELB Primary Antibody

抗原表位
19

16

15

14

10

6

5

5

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 530-579, pSer552

原理

RelB (phospho Ser552) Antibody

特异性

Phospho-RelB (S552) Polyclonal Antibody detects endogenous levels of RelB protein only when phosphorylated at S552.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

纯度

> 95 %

免疫原

The antiserum was produced against synthesized peptide derived from human RelB around the phosphorylation site of Ser552. AA range:530-579

亚型

IgG
anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 1-579) antibody
RELB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 1-579) antibody
RELB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibody
KD Validated RELB 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB925 unconjugated Recombinant Antibody

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 273-443) antibody
RELB 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2E4B1 unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (C-Term) antibody
RELB 适用: 人, 小鼠 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 248-492) antibody
RELB 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibody
KD Validated RELB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5070 unconjugated Recombinant Antibody

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (AA 161-260) antibody
RELB 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) antibody
RELB 适用: 人 WB 宿主: 小鼠 Monoclonal 4C5 unconjugated

anti-V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (N-Term) antibody
RELB 适用: 人, 犬, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C/1 year

有效期

12 months
抗原

RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))

别名

RelB

背景

Synonyms: RELB, Transcription factor RelB, I-Rel
Background: caution:Was originally (PubMed:1577270) thought to inhibit the transcriptional activity of nuclear factor NF-kappa-B.,domain:Both N- and C-terminal domains are required for transcriptional activation.,function:NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49.,induction:By mitogens.,PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation.,similarity:Contains 1 RHD (Rel-like) domain.,subunit:Component of the NF-kappa-B RelB-p50 complex. Component of the NF-kappa-B RelB-p52 complex. Self-associates, the interaction seems to be transient and may prevent degradation allowing for heterodimer formation with p50 or p52. Interacts with NFKB1/p50, NFKB2/p52 and NFKB2/p100. Interacts with NFKBID.,
Gene Name: RELB
Protein Name: Transcription factor RelB

分子量

62 kDa

基因ID

5971

OMIM

604758

UniProt

Q01201

途径

NF-kappaB Signaling, RTK signaling