c-Rel 抗体 (pSer503)
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北京 101111
Quick Overview for c-Rel 抗体 (pSer503) (ABIN1531963)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-519, pSer503
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原理
- c-Rel (phospho Ser503) Antibody
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特异性
- Phospho-c-Rel (S503) Polyclonal Antibody detects endogenous levels of c-Rel protein only when phosphorylated at S503.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Rel around the phosphorylation site of Ser503. AA range:470-519
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- Rel
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背景
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Synonyms: REL; Proto-oncogene c-Rel
Background: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014],
Gene Name: REL
Protein Name: Proto-oncogene c-Rel
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分子量
- 68 kDa
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基因ID
- 5966
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OMIM
- 164910
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UniProt
- Q04864
抗原
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