IRS1 抗体 (pSer307)
(1 reference)Quick Overview for IRS1 抗体 (pSer307) (ABIN1531876)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 274-323, pSer307
-
特异性
-
IRS-1 (Phospho-Ser307) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Ser307.
PhosphorylationH:S307 M:S302 R:S302
-
纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser307.
-
亚型
- IgG
-
-
anti-Insulin Receptor Substrate 1 (IRS1) (pSer639) antibody
IRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer312) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer636) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 1041-1242) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer307) antibodyIRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (AA 106-122), (N-Term) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer636) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (Ser312) antibodyIRS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer307) antibodyIRS1 适用: 人, 小鼠, 大鼠, 山羊 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 1 (IRS1) (pSer1101) antibodyIRS1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000
-
说明
-
Unigene-Number: Hs.471508 (NCBI Gene Symbol: IRS1)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable at -20°C for at least 1 year.
-
有效期
- 12 months
-
-
-
: "Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e97868, (2014) (PubMed).
-
: "Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e97868, (2014) (PubMed).
-
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
-
别名
- IRS-1
-
背景
-
Synonyms: Insulin receptor substrate-1, IRS-1, IRS1
NCBI Gene Symbol: IRS1
-
分子量
- 131 kDa
-
基因ID
- 3667
-
OMIM
- 125853
-
UniProt
- P35568
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
-
