Estrogen Receptor alpha 抗体 (pSer167)
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Quick Overview for Estrogen Receptor alpha 抗体 (pSer167) (ABIN482448)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-185, pSer167
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原理
- ERα (phospho Ser167) Antibody
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特异性
- Phospho-ERα (S167) Polyclonal Antibody detects endogenous levels of ERα protein only when phosphorylated at S167.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha around the phosphorylation site of Ser167. AA range:136-185
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亚型
- IgG
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anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 适用: 人 FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) antibodyESR1 适用: 人 WB, IHC, FACS, ICC, IP 宿主: 小鼠 Monoclonal 119-13 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 425-595) antibodyESR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibodyESR1 适用: 大鼠 WB, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer118) antibodyESR1 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- Estrogen Receptor-alpha
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背景
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Synonyms: ESR1, ESR, NR3A1, Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],
Gene Name: ESR1
Protein Name: Estrogen receptor
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分子量
- 66 kDa
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基因ID
- 2099
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OMIM
- 133430
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UniProt
- P03372
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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