BAX 抗体 (pThr167)
Quick Overview for BAX 抗体 (pThr167) (ABIN1531490)
抗原
See all BAX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-182, pThr167
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特异性
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Bax (Phospho-Thr167) Antibody detects endogenous levels of Bax only when phosphorylated at Thr167.
PhosphorylationH:T167 M:T167 R:T167
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167.
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亚型
- IgG
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应用备注
- IF: 1:100~1:500 ELISA: 1:40000
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说明
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Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." in: Phytotherapy research : PTR, (2015) (PubMed).
: "Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124742, (2015) (PubMed).
: "Asenapine increases nitric oxide release and protects porcine coronary artery endothelial cells against peroxidation." in: Vascular pharmacology, Vol. 60, Issue 3, pp. 127-41, (2014) (PubMed).
: "Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats." in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 20, Issue 3, pp. 361-75, (2014) (PubMed).
: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).
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: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." in: Phytotherapy research : PTR, (2015) (PubMed).
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- BAX (BCL2-Associated X Protein (BAX))
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别名
- Bax
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背景
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Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4
NCBI Gene Symbol: BAX
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分子量
- 21 kDa
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基因ID
- 581
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OMIM
- 600040
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UniProt
- Q07812
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途径
- p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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