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BAX 抗体 (pThr167)

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1531490
发货至: 中国

Quick Overview for BAX 抗体 (pThr167) (ABIN1531490)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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人, 小鼠, 大鼠

宿主

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  • 96
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克隆类型

  • 168
  • 90
多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    • 25
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    AA 133-182, pThr167

    特异性

    Bax (Phospho-Thr167) Antibody detects endogenous levels of Bax only when phosphorylated at Thr167.

    PhosphorylationH:T167 M:T167 R:T167

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167.

    亚型

    IgG
  • 应用备注

    IF: 1:100~1:500 ELISA: 1:40000

    说明

    Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • Grossini, Marotta, Farruggio, Sigaudo, Qoqaiche, Raina, de Giuli, Mary, Vacca, Pollastro: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." in: Phytotherapy research : PTR, (2015) (PubMed).

    Grossini, Bellofatto, Farruggio, Sigaudo, Marotta, Raina, De Giuli, Mary, Pollesello, Minisini, Pirisi, Vacca: "Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124742, (2015) (PubMed).

    Grossini, Gramaglia, Farruggio, Bellofatto, Anchisi, Mary, Vacca, Zeppegno: "Asenapine increases nitric oxide release and protects porcine coronary artery endothelial cells against peroxidation." in: Vascular pharmacology, Vol. 60, Issue 3, pp. 127-41, (2014) (PubMed).

    Grossini, Pollesello, Bellofatto, Sigaudo, Farruggio, Origlia, Mombello, Mary, Valente, Vacca: "Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats." in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 20, Issue 3, pp. 361-75, (2014) (PubMed).

    Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).

  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    Bax

    背景

    Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4

    NCBI Gene Symbol: BAX

    分子量

    21 kDa

    基因ID

    581

    OMIM

    600040

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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