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YAP1 抗体 (pSer127)

The 兔 多克隆 anti-YAP1 antibody is suitable to detect YAP1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB, IHC, IF 和 ELISA.
产品编号 ABIN1531475
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for YAP1 抗体 (pSer127) (ABIN1531475)

抗原

See all YAP1 抗体
YAP1 (Yes-Associated Protein 1 (YAP1))

适用

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人, 小鼠, 大鼠, 猴

宿主

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兔

克隆类型

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多克隆

标记

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This YAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    AA 93-142, pSer127

    原理

    YAP (phospho Ser127) Antibody

    特异性

    Phospho-YAP (S127) Polyclonal Antibody detects endogenous levels of YAP protein only when phosphorylated at S127.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human YAP around the phosphorylation site of Ser127. AA range:93-142

    亚型

    IgG
  • 应用备注

    IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    YAP1 (Yes-Associated Protein 1 (YAP1))

    别名

    YAP

    背景

    Synonyms: YAP1, YAP65, Yorkie homolog, 65 kDa Yes-associated protein, YAP65

    Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],

    Gene Name: YAP1

    Protein Name: Yorkie homolog

    分子量

    48 kDa

    基因ID

    10413

    OMIM

    606608

    UniProt

    P46937

    途径

    MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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