JNK 抗体 (pThr183)
Quick Overview for JNK 抗体 (pThr183) (ABIN481942)
抗原
See all JNK (MAPK8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200, pThr183
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特异性
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JNK1/2/3 (Phospho-Thr183+Tyr185) Antibody detects endogenous levels of JNK1/2/3 only when phosphorylated at Thr183 and Tyr185.
PhosphorylationH:T183/Y185 M:T183/Y185 R:T183/Y185
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Thr183 and Tyr185.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 ELISA: 1:10000
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说明
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Unigene-Number: Hs.138211, Hs.654461, Hs.125503 (NCBI Gene Symbol: MAPK8)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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别名
- JNK1/2/3
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背景
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Synonyms: JNK-46, JNK1-alpha-2, MAPK8, MK08, Mitogen-activated protein kinase 8, PRKM8, SAPK gamma, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, kinase JNK1, p54 gamma
NCBI Gene Symbol: MAPK8
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分子量
- 48 kDa
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基因ID
- 5599, 5601, 5602
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OMIM
- 601158
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UniProt
- P45983, P45984, P53779
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
抗原
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