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c-MET 抗体 (AA 25-325)

MET 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1513199
发货至: 中国
  • 抗原 See all c-MET (MET) 抗体
    c-MET (MET) (Met Proto-Oncogene (MET))
    抗原表位
    • 43
    • 29
    • 28
    • 21
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-325
    适用
    • 240
    • 143
    • 97
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 212
    • 38
    • 3
    • 2
    克隆类型
    • 208
    • 47
    多克隆
    标记
    • 125
    • 20
    • 12
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This c-MET antibody is un-conjugated
    应用范围
    • 178
    • 104
    • 43
    • 43
    • 29
    • 27
    • 26
    • 21
    • 12
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    ECKEALAKSE MNVNMKYQLP NFTAETPIQN VILHEHHIFL GATNYIYVLN EEDLQKVAEY KTGPVLEHPD CFPCQDCSSK ANLSGGVWKD NINMALVVDT YYDDQLISCG SVNRGTCQRH VFPHNHTADI QSEVHCIFSP QIEEPSQCPD CVVSALGAKV LSSVKDRFIN FFVGNTINSS YFPDHPLHSI SVRRLKETKD GFMFLTDQSY IDVLPEFRDS YPIKYVHAFE SNNFIYFLTV QRETLDAQTF HTRIIRFCSI NSGLHSYMEM PLECILTEKR KKRSTKKEVF NILQAAYVSK P
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 25-325 of human MET (NP_001120972.1).
    亚型
    IgG
    Top Product
    Discover our top product MET Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    c-MET (MET) (Met Proto-Oncogene (MET))
    别名
    MET (MET 产品)
    别名
    AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody
    背景
    This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.,MET,AUTS9,DFNB97,HGFR,RCCP2,c-Met,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Stem Cells,MET
    分子量
    85 kDa/155 kDa/157 kDa
    基因ID
    4233
    UniProt
    P08581
    途径
    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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