BIRC7 抗体 (AA 162-211)
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北京 101111
Quick Overview for BIRC7 抗体 (AA 162-211) (ABIN1453581)
抗原
See all BIRC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 162-211
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原理
- ML-IAP Antibody
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特异性
- ML-IAP Polyclonal Antibody detects endogenous levels of ML-IAP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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别名
- ML-IAP
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背景
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Synonyms: BIRC7, KIAP, LIVIN, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50
Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],
Gene Name: BIRC7
Protein Name: Baculoviral IAP repeat-containing protein 7
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分子量
- 32 kDa
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基因ID
- 79444
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OMIM
- 605737
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UniProt
- Q96CA5
抗原
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