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CD51 抗体 (AA 755-804)

The 兔 多克隆 anti-CD51 antibody (ABIN1453524) specifically detects CD51 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1453524
发货至: 中国
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Quick Overview for CD51 抗体 (AA 755-804) (ABIN1453524)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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  • 5
  • 5
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人, 小鼠

宿主

  • 117
  • 63
  • 13
兔

克隆类型

  • 119
  • 73
多克隆

标记

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This CD51 antibody is un-conjugated

应用范围

  • 111
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 26
    • 16
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 755-804

    原理

    Integrin αV Antibody

    特异性

    Integrin αV Polyclonal Antibody detects endogenous levels of Integrin αV protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human Integrin alphaV. AA range:755-804

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    Integrin AlphaV

    背景

    Synonyms: ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51

    Background: integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

    Gene Name: ITGAV

    Protein Name: Integrin alpha-V

    分子量

    116 kDa

    基因ID

    3685

    OMIM

    193210

    UniProt

    P06756

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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