TANK 抗体 (AA 171-220)
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Quick Overview for TANK 抗体 (AA 171-220) (ABIN1450959)
抗原
See all TANK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220
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原理
- TANK Antibody
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特异性
- TANK Polyclonal Antibody detects endogenous levels of TANK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TANK. AA range:171-220
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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别名
- I-TRAF
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背景
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Synonyms: TANK, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, I-TRAF
Background: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example,The protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
Gene Name: TANK
Protein Name: TRAF family member-associated NF-kappa-B activator
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分子量
- 47 kDa
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基因ID
- 10010
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OMIM
- 603893
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UniProt
- Q92844
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途径
- p53 Pathway, TLR signaling, Activation of Innate immune Response
抗原
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