LKB1 抗体 (pSer334)
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北京 101111
Quick Overview for LKB1 抗体 (pSer334) (ABIN1450431)
抗原
See all LKB1 (STK11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-349, pSer334
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原理
- LKB1 (phospho Ser334) Antibody
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特异性
- Phospho-LKB1 (S334) Polyclonal Antibody detects endogenous levels of LKB1 protein only when phosphorylated at S334.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human LKB1 around the phosphorylation site of Ser334. AA range:300-349
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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别名
- LKB1
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背景
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Synonyms: STK11, LKB1, PJS, Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19
Background: This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],
Gene Name: STK11
Protein Name: Serine/threonine-protein kinase STK11
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分子量
- 48 kDa
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基因ID
- 6794
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OMIM
- 175200
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UniProt
- Q15831
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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