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ITK 抗体 (pTyr512)

The 兔 多克隆 anti-ITK antibody (ABIN1450332) specifically detects ITK in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1450332
发货至: 中国
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Quick Overview for ITK 抗体 (pTyr512) (ABIN1450332)

抗原

See all ITK 抗体
ITK (IL2-Inducible T-Cell Kinase (ITK))

适用

  • 83
  • 24
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人, 小鼠

宿主

  • 95
  • 6
  • 2
兔

克隆类型

  • 86
  • 17
多克隆

标记

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This ITK antibody is un-conjugated

应用范围

  • 66
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  • 24
  • 14
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  • 6
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 18
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    AA 478-527, pTyr512

    原理

    Emt (phospho Tyr512) Antibody

    特异性

    Phospho-Emt (Y512) Polyclonal Antibody detects endogenous levels of Emt protein only when phosphorylated at Y512.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human ITK around the phosphorylation site of Tyr512. AA range:478-527

    亚型

    IgG
  • 应用备注

    WB 1:500-2000 ,IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ITK (IL2-Inducible T-Cell Kinase (ITK))

    别名

    ITK

    背景

    Synonyms: ITK, EMT, LYK, Tyrosine-protein kinase ITK/TSK, Interleukin-2-inducible T-cell kinase, IL-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk

    Background: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008],

    Gene Name: ITK

    Protein Name: Tyrosine-protein kinase ITK/TSK

    分子量

    71 kDa

    基因ID

    3702

    OMIM

    186973

    UniProt

    Q08881

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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