ITK 抗体 (pTyr512)
Quick Overview for ITK 抗体 (pTyr512) (ABIN1450332)
抗原
See all ITK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 478-527, pTyr512
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特异性
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ITK (Phospho-Tyr512) Antibody detects endogenous levels of ITK only when phosphorylated at Tyr512.
PhosphorylationH:Y512, M:Y517
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ITK around the phosphorylation site of Tyr512.
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亚型
- IgG
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应用备注
- IHC: 1:50~1:100 ELISA: 1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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- ITK (IL2-Inducible T-Cell Kinase (ITK))
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别名
- ITK
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背景
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Synonyms: EMT, IL-2-inducible T-cell kinase, IL2-inducible T-cell kinase, ITK/TSK, Kinase EMT, kinase Itk, LYK, Lyk, T-cell-specific kinase, TLK, TSK
NCBI Gene Symbol: ITK
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分子量
- 71 kDa
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基因ID
- 3702
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OMIM
- 186973
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UniProt
- Q08881
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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