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- 抗原 See all ANKLE2 products
- ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANKLE2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CYSPSDRQSW PSPAVKGRFK SQLPDLSGPH SYSPGRNSVA GSNPAKPGLG
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Purified using peptide immunoaffinity column
- 免疫原
- Synthetic peptide directed towards the middle region of human KIAA0692
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anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (AA 350-450) antibody
ANKLE2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (AA 864-913) antibodyANKLE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (Internal Region) antibodyANKLE2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 小鸡 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- 抗原
- ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
- 别名
- ANKLE2 / KIAA0692 (ANKLE2 产品)
- 别名
- KIAA0692 antibody, LEMD7 antibody, Lem4 antibody, 1110001J12Rik antibody, AI661024 antibody, D5Ertd585e antibody, RGD1310191 antibody, ankyrin repeat and LEM domain containing 2 antibody, ANKLE2 antibody, Ankle2 antibody
- 背景
- ANKLE2 or KIAA0692 is a single-pass membrane protein. It contains 1 ANK repeat and 1 LEM domain. It contains 1 RING-type zinc finger. It is involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. ANKLE2 coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.Synonyms: Ankyrin repeat and LEM domain-containing protein 2
- 基因ID
- 23141
- NCBI登录号
- NP_055929
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