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GCLM 抗体 (N-Term)

GCLM 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal AT2D12 unconjugated
产品编号 ABIN1449395
发货至: 中国
  • 抗原 See all GCLM 抗体
    GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
    抗原表位
    • 11
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-274, N-Term
    适用
    • 65
    • 34
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 59
    • 6
    小鼠
    克隆类型
    • 51
    • 14
    单克隆
    标记
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This GCLM antibody is un-conjugated
    应用范围
    • 40
    • 28
    • 25
    • 19
    • 16
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein-G affinity chromatography
    免疫原
    Recombinant human GCLM (1-274aa) purified from E. coli
    克隆位点
    AT2D12
    亚型
    IgG1
    Top Product
    Discover our top product GCLM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
    别名
    GCLM / GLCLR (GCLM 产品)
    别名
    Glclr antibody, GLCLR antibody, id:ibd3182 antibody, wu:fi24c07 antibody, zgc:55903 antibody, AI649393 antibody, Gcmc antibody, glutamate-cysteine ligase regulatory subunit antibody, glutamate cysteine ligase, modifier subunit antibody, glutamate-cysteine ligase modifier subunit antibody, glutamate-cysteine ligase, modifier subunit antibody, glutamate-cysteine ligase, modifier subunit L homeolog antibody, PTRG_09814 antibody, Gclm antibody, GCLM antibody, gclm antibody, gclm.L antibody
    背景
    GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.Synonyms: GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate-cysteine ligase modifier subunit, Glutamate-cysteine ligase regulatory subunit
    基因ID
    2730
    NCBI登录号
    NP_002052
    UniProt
    P48507
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