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KLF4 抗体 (C-Term)

KLF4 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 小鼠 Monoclonal 4G6E11 unconjugated
产品编号 ABIN1449394
发货至: 中国
  • 抗原 See all KLF4 抗体
    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
    抗原表位
    • 13
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    C-Term
    适用
    • 111
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    人, 小鼠, 大鼠
    宿主
    • 92
    • 23
    • 1
    小鼠
    克隆类型
    • 83
    • 33
    单克隆
    标记
    • 75
    • 8
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    • 5
    • 1
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    This KLF4 antibody is un-conjugated
    应用范围
    • 86
    • 59
    • 50
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    • 8
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    A 20 amino acid synthetic peptide near the carboxy terminus of Human KLF4 (AM50015CP- N)
    克隆位点
    4G6E11
    亚型
    IgG1
    Top Product
    Discover our top product KLF4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
    别名
    KLF4 (KLF4 产品)
    别名
    EZF antibody, GKLF antibody, Gklf antibody, Zie antibody, KLF4 antibody, biklf antibody, biklf-A antibody, Kruppel like factor 4 antibody, Kruppel-like factor 4 (gut) antibody, Kruppel-like factor 4 antibody, Kruppel-like factor 4 (gut) L homeolog antibody, KLF4 antibody, Klf4 antibody, klf4 antibody, klf4.L antibody
    背景
    KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.Synonyms: EZF, Epithelial zinc finger protein EZF, GKL, Gut-enriched krueppel-like factor, Krueppel-like factor 4
    基因ID
    9314
    UniProt
    O43474
    途径
    Peptide Hormone Metabolism, Stem Cell Maintenance
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