电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ICAM-3/CD50 抗体

ICAM3 适用: 人 FACS 宿主: 小鼠 Monoclonal YUK2 unconjugated
产品编号 ABIN1449265
发货至: 中国
  • 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    适用
    • 112
    • 3
    • 2
    • 2
    宿主
    • 68
    • 43
    • 1
    小鼠
    克隆类型
    • 72
    • 40
    单克隆
    标记
    • 61
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM-3/CD50 antibody is un-conjugated
    应用范围
    • 62
    • 49
    • 47
    • 34
    • 26
    • 25
    • 22
    • 13
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human CD50 antigen.
    纯化方法
    Protein A agarose
    免疫原
    Human myeloma cell line (RPMI8226)
    克隆位点
    YUK2
    亚型
    IgG1
    Top Product
    Discover our top product ICAM3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    别名
    CD50 / ICAM3 (ICAM3 产品)
    别名
    CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
    背景
    Intercellular adhesion molecules (ICAMs) are type I transmem brane glycoproteins, which contain 2-9 immunoglobulin-like C2-type domains, and bind to lymphocyte function- associated antigen-1 (LFA-1, also known as a L/ ß 2 or CD11a/CD18). ICAM-3 (CD50) is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. ICAM-3 is the most important ligand for LFA-1 in the initiation of the immune response because the expression of ICAM-1 (CD54) and ICAM-2 (CD102) on resting leukocytes is very low or not at all. Previous studies suggest that ICAM-3 acts as a biologically significant molecule playing a role in HIV-1 transcription and replication, particularly in resting CD4 + T cells. It has been suggested that dendritic cell-specific ICAM grabbing nonintegrin (DC-SIGN, CD209), a C-type lectin of macrophages and DCs, is an additional ligand of ICAM-3. The interaction of DC-SIGN with ICAM-3 establishes initial contact between dendritic cells and resting T-cells during antigen presentation.Synonyms: CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3
    基因ID
    3385
    NCBI登录号
    NP_002153
    UniProt
    P32942
You are here:
客服