SF3B1 抗体 (AA 98-198)
(1 reference)-
- 抗原 See all SF3B1 抗体
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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抗原表位
- AA 98-198
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SF3B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with Sap155.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse
- 纯化方法
- Protein A agarose
- 免疫原
- Recombinant GST-Sap155 (98 a.a.- 198 a.a.)
- 克隆位点
- 16
- 亚型
- IgG2b
- Top Product
- Discover our top product SF3B1 Primary Antibody
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anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibody
SF3B1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibodySF3B1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 6C7 unconjugated Recombinant Antibody
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 1-144) antibodySF3B1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 186-378) antibodySF3B1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 374-402), (N-Term) antibodySF3B1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33758 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 287-336) antibodySF3B1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 山羊, 兔, 小鸡, Hamster, Pig, 非洲爪蟾, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibodySF3B1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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: "Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability." in: Cell reports, Vol. 28, Issue 6, pp. 1551-1563.e7, (2020) (PubMed).
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: "Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability." in: Cell reports, Vol. 28, Issue 6, pp. 1551-1563.e7, (2020) (PubMed).
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- 抗原
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- 别名
- SF3B1 / SAP155 (SF3B1 产品)
- 别名
- Cus1 antibody, SAP145 antibody, SF3B145 antibody, SF3b1 antibody, SF3b150 antibody, Hsh155 antibody, MDS antibody, PRP10 antibody, PRPF10 antibody, SAP155 antibody, SF3b155 antibody, 155kDa antibody, 2810001M05Rik antibody, AA409119 antibody, Prp10 antibody, TA-8 antibody, Targ4 antibody, hsh155 antibody, prp10 antibody, prpf10 antibody, sap155 antibody, SF3B1 antibody, Sap155 antibody, wu:fb99f09 antibody, splicing factor 3b subunit 2 antibody, splicing factor 3b subunit 1 antibody, splicing factor 3b, subunit 1 antibody, splicing factor 3b subunit 1 S homeolog antibody, SF3B2 antibody, SF3B1 antibody, Sf3b1 antibody, sf3b1.S antibody, sf3b1 antibody
- 背景
- SF3 is a U2 snRNP-associated protein complex essential for spliceosome assembly and splicing catalysis of the majo r spliceosome. SF3 contains the Spliceosome-Associated Proteins, Sap 49, 130, 145, and 155. Sap155/Sf3b1 is an essential subunit of the U2 snRNP for mRNA splicing and has also been identified in the minor (U12-dependent) sp liceosome. Sap155 interacts with the mammalian PcG (Polycomb group) proteins, Mel18 and Ring1B by the yeast two hybrid system. Sap155 contains numerous Cdk consensus phosphorylation sites in its N terminus and is phosphorylated prior to catal ytic step II of the splicing pathway. Sap155 serves as a substrate for cyclin E-cdk2 in vitro , suggesting that pre-mRNA splicing may be linked to the cell cycle machiner y in mammalian cells.Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit, SAP 155, SAP-155, SF3b155, Spliceosome-associated protein 155, Splicing factor 3B subunit 1
- 分子量
- 155 kDa
- 基因ID
- 23451
- NCBI登录号
- NP_036565
- UniProt
- O75533
- 途径
- Chromatin Binding
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