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CD52 抗体

CD52 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal BTG-2G unconjugated
产品编号 ABIN1449230
发货至: 中国
  • 抗原 See all CD52 抗体
    CD52
    适用
    • 60
    • 11
    • 7
    • 5
    • 4
    • 1
    小鼠
    宿主
    • 23
    • 19
    • 19
    • 1
    • 1
    大鼠
    克隆类型
    • 46
    • 11
    • 3
    单克隆
    标记
    • 32
    • 8
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD52 antibody is un-conjugated
    应用范围
    • 48
    • 20
    • 19
    • 16
    • 14
    • 13
    • 12
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    This antibody reacts with mouse CAMPATH-1/CD52.
    纯化方法
    Protein G agarose
    免疫原
    Mouse IL-2R alpha-TGM splenocyte
    克隆位点
    BTG-2G
    亚型
    IgG2a
    Top Product
    Discover our top product CD52 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    CD52
    别名
    CD52 / CAMPATH-1 (CD52 产品)
    别名
    CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody
    背景
    CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
    基因ID
    23833
    NCBI登录号
    NP_038734
    UniProt
    Q64389
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