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PRPF3 抗体

PRPF3 适用: 人, 小鼠, 大鼠, Hamster WB, IF, IP 宿主: 大鼠 Monoclonal 4-00E-003 unconjugated
产品编号 ABIN1449201
发货至: 中国
  • 抗原 See all PRPF3 抗体
    PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))
    适用
    • 27
    • 19
    • 18
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Hamster
    宿主
    • 25
    • 2
    大鼠
    克隆类型
    • 25
    • 2
    单克隆
    标记
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRPF3 antibody is un-conjugated
    应用范围
    • 13
    • 10
    • 7
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Prp3.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Hamster, Rat
    纯化方法
    Protein G agarose
    免疫原
    Human recombinant full-length GSTPrp3
    克隆位点
    4-00E-003
    亚型
    IgG2a
    Top Product
    Discover our top product PRPF3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))
    别名
    PRPF3 (PRPF3 产品)
    别名
    HPRP3 antibody, HPRP3P antibody, wu:fa11f05 antibody, PRPF3 antibody, PRP3 antibody, Prp3p antibody, RP18 antibody, SNRNP90 antibody, 3632413F13Rik antibody, PRP3 pre-mRNA processing factor 3 homolog (yeast) antibody, pre-mRNA processing factor 3 antibody, pre-mRNA processing factor 3 S homeolog antibody, PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) antibody, prpf3 antibody, PRPF3 antibody, prpf3.S antibody, Prpf3 antibody
    背景
    Retinitis pigmentosa (RP) is an inheritable disease characterized by progressive retinal degeneration and loss of rod photoreceptor cells, leading to total blindness. Recently three genes responsible for autosomal dominant RP (HPRP3, PRPF31, and PRPC8) have been identified as the human orthologues of the yeast genes PRP3, PRP31, and PRP8, respectively. The removal of introns from nuclear pre-mRNAs occurs on spliceosomes, which consist of 4 small nuclear ribonucleoprotein (snRNP) particles and a number of transiently associated splicing factors. All three PRP (pre-mRNA processing factor) genes are involved in the function of the U4/U6,U5 tri-snRNP, the spliceosome component required for the transition to a catalytically active state. In mammals, the 63 kDa HPRP3 is thought to recruit HPRP4 to the U4/U6 snRNP. In yeast, PRP3 and PRP4 genetically interact, and physical interactions between Prp3p and Prp4p proteins are required for association of Prp3p and Prp4p with U4/U6.Synonyms: HPRP3, PRP3, Pre-mRNA-splicing factor 3, U4/U6 small nuclear ribonucleoprotein Prp3, U4/U6 snRNP 90 kDa protein
    分子量
    80 kDa
    基因ID
    9129
    NCBI登录号
    NP_004689
    UniProt
    O43395
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