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- 抗原 See all IL12RB1 抗体
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL12RB1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with CD212.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein A agarose
- 免疫原
- B300-19 cells transfected with the vector expressing an IL-12R beta1/Tac fusion protein
- 克隆位点
- TOS
- 亚型
- IgG1
- Top Product
- Discover our top product IL12RB1 Primary Antibody
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anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 420-470) antibody
IL12RB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (Internal Region) antibodyIL12RB1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 37-234) antibodyIL12RB1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 197-348) antibodyIL12RB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 119-280) antibodyIL12RB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 别名
- CD212 / IL12RB1 (IL12RB1 产品)
- 别名
- Il12rb antibody, IL12RB1 antibody, IL-12R antibody, CD212 antibody, IL-12R-BETA1 antibody, IL12RB antibody, IL-12R[b] antibody, interleukin 12 receptor subunit beta 1 antibody, interleukin 12 receptor, beta 1 antibody, Il12rb1 antibody, IL12RB1 antibody
- 背景
- A functional interleukin 12 receptor complex is composed of two ß-type cytokine receptor subunits, IL-12R ß1 (100 kDa) and IL-12R ß2 (130 kDa), each independently exhibiting a low affinity for IL-12. Co-expression leads to the formation of high-affinity IL-12-binding sites and reconstitution of IL-12-dependent signaling. IL-12R ß1 is a member of the hemopoietin receptor superfamily, bearing strong homology to gp130. IL-12 receptors are expressed primarily on activated T cells and natural killer (NK) cells, and activation of human PBMCs results in the up-regulation of IL-12R ß1 expression and IL-12 binding. Alternately, individuals that are genetically deficient in IL-12R ß1 produce greatly reduced IFN-? levels compared to healthy individuals. IL-12 induces tyrosine phosphorylation of an 85 kDa component of the IL-12 receptor complex that associates with the IL-12R ß1 subunit.Synonyms: IL-12 receptor beta, IL-12R-beta-1, IL-12RB1, IL12 receptor beta component, Interleukin-12 receptor beta-1 chain
- 基因ID
- 3594
- NCBI登录号
- NP_005526
- UniProt
- P42701
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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