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Connexin 43/GJA1 抗体 (C-Term)

This 山羊多克隆 antibody specifically detects Connexin 43/GJA1 in WB, IF, IHC (p) 和 IHC (fro). It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, 猴, Cow, 兔, 小鸡, Pig, 豚鼠, 马, 绵羊, Hamster, 山羊, Avian, Cat 和驴. It has been mentioned in 3+ publications

Immunohistochemistry (IHC) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody (ABIN1440034) (Connexin 43/GJA1 抗体 (C-Term))

IHC

Immunostaining of primary RPE cells With CX43 Ab at 1/100 dilution. (Connexin 43/GJA1 抗体 (C-Term))

ISt

Immunofluorescence (IF) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody (ABIN1440034) (Connexin 43/GJA1 抗体 (C-Term))

IHC

9 images

(3 references)

产品编号 ABIN1440034

发货至: 中国

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Quick Overview for Connexin 43/GJA1 抗体 (C-Term) (ABIN1440034)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

人, 小鼠, 大鼠, 犬, 猴, Cow, 兔, 小鸡, Pig, 豚鼠, 马, 绵羊, Hamster, 山羊, Avian, Cat, 驴

宿主

山羊

克隆类型

多克隆

标记

This Connexin 43/GJA1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

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C-Term

原理

Anti-CX43

序列

VKDRVKGRSD PYHATTGPLS PSKDCGSPKY AYFNGCSSPT APLSPMSPPG YKLVTGDRNN SSCRNYNKQA SEQNWANYSA EQNRMGQAGS TISNSHAQPF DFPDDNQNAK KVAAGHELQP LAIVDQRPSS RASSRASSRP RPDDLEI

特异性

Detects endogenous levels of total connexin 43.

产品特性

Gap junction protein, alpha 1, 43 kDa

纯化方法

Epitope affinity purified

免疫原

Purified recombinant peptide derived from within residues 230 aa to the C-terminus of rat CX43 produced in E. coli.

亚型

IgG
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibody
GJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 310-390) antibody
GJA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138) antibody
GJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 351-367) antibody
GJA1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 211-260) antibody
GJA1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 244-382) antibody
GJA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibody
GJA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 331-345), (Intracellular) antibody
GJA1 适用: 人 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
GJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (N-Term) antibody
GJA1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:800, IHC-F:1:250-1:800

限制

仅限研究用
浓度

4 mg/mL

缓冲液

PBS, 20 % glycerol and 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

The antibody solution should be gently mixed before use.

储存条件

4 °C,-20 °C

储存方法

For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Martins-Marques, Pinho, Zuzarte, Oliveira, Pereira, Sluijter, Gomes, Girao: "Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin." in: Journal of extracellular vesicles, Vol. 5, pp. 32538, (2016) (PubMed).

Martins-Marques, Anjo, Pereira, Manadas, Girão: "Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 11, pp. 3040-55, (2016) (PubMed).

Ribeiro-Rodrigues, Catarino, Marques, Ferreira, Martins-Marques, Pereira, Girão: "AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4629-41, (2015) (PubMed).
抗原

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

别名

CX43

背景

Goat polyclonal to connexin 43, which is a member of the connexin family. Cx43 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. This protein is the major protein of gap junctions in embryonic development and in the heart that are thought to have a crucial role in the synchronized contraction of the heart.
AVSD3, CX43, DFNB38, gap junction protein, alpha 1, 43 kDa, GJA1, GJAL HSS, HLHS1, ODDD antibody.

途径

MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization