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Peroxiredoxin 2 抗体 (AA 131-198) (Cy5)

PRDX2 适用: 人, 大鼠 FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1416162
发货至: 中国
  • 抗原 See all Peroxiredoxin 2 (PRDX2) 抗体
    Peroxiredoxin 2 (PRDX2)
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-198
    适用
    • 60
    • 36
    • 26
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 56
    • 6
    • 1
    克隆类型
    • 50
    • 13
    多克隆
    标记
    • 29
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Peroxiredoxin 2 antibody is conjugated to Cy5
    应用范围
    • 30
    • 19
    • 14
    • 13
    • 13
    • 12
    • 9
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Peroxiredoxin-2
    亚型
    IgG
    Top Product
    Discover our top product PRDX2 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Peroxiredoxin 2 (PRDX2)
    别名
    Peroxiredoxin 2 (PRDX2 产品)
    别名
    NKEF-B antibody, NKEFB antibody, PRP antibody, PRX2 antibody, PRXII antibody, PTX1 antibody, TDPX1 antibody, TPX1 antibody, TSA antibody, AL022839 antibody, Band-8 antibody, NkefB antibody, PrxII antibody, TDX1 antibody, TPx antibody, TPx-B antibody, TR antibody, Tdpx1 antibody, Torin antibody, nkefb antibody, prx-2 antibody, prx2 antibody, prxii antibody, tdpx1 antibody, tpx1 antibody, peroxiredoxin 2 antibody, peroxiredoxin 2 L homeolog antibody, PRDX2 antibody, Prdx2 antibody, prdx2.L antibody
    背景

    Synonyms: MGC4104, Natural killer cell enhancing factor B, Natural killer cell-enhancing factor B, Natural Killer Enhancing Factor B, NKEF B, NKEF-B, NKEFB, Peroxiredoxin-2, PRDX 2, PRDX2, PRDX2_HUMAN, PRP, PRX2, PRXII, TDPX1, Thiol Specic Antioxidant 1, Thiol specic antioxidant protein, Thiol-specic antioxidant protein, Thioredoxin Dependent Peroxide Reductase 1, Thioredoxin Peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Torin, TPX1, TSA.

    Background: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

    基因ID
    7001
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