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CSDC2 抗体 (AA 21-120) (Cy3)

CSDC2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1411425
发货至: 中国
  • 抗原 See all CSDC2 抗体
    CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 34
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 2
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSDC2 antibody is conjugated to Cy3
    应用范围
    • 34
    • 19
    • 16
    • 12
    • 12
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PIPPIN
    亚型
    IgG
    Top Product
    Discover our top product CSDC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))
    别名
    CSDC2/PIPPIN (CSDC2 产品)
    别名
    pippin antibody, csdc2 antibody, zgc:91826 antibody, PIPPIN antibody, dJ347H13.2 antibody, AI415250 antibody, AI481750 antibody, Pippin antibody, cold shock domain containing C2, RNA binding antibody, cold shock domain containing C2 antibody, cold shock domain containing C2, RNA binding a antibody, cold shock domain containing C2 L homeolog antibody, CSDC2 antibody, csdc2 antibody, csdc2a antibody, csdc2.L antibody, Csdc2 antibody
    背景

    Synonyms: Cold shock domain containing C2 RNA binding, Cold shock domain containing protein C2, Cold shock domain-containing protein C2, CSDC 2, Csdc2, CSDC2_HUMAN, dJ347H13.2, PIPPIN, RNA binding protein PIPPin, RNA-binding protein PIPPin.

    Background: PIPPIN is a Y-box protein (also called cold-shock (CSD) domain-containing protein) and belongs to a family of highly conserved RNA-binding transcriptional regulators. Predominantly expressed in brain cells and localizing to the nucleus and the cytoplasm, PIPPIN contains two RNA-binding motifs, namely PIP1 and PIP2, and one CSD domain. PIPPIN functions as a nucleic acid binding regulatory factor and is believed to participate in brain maturation. More specifically, PIPPIN binds to the 3?-UTR ends of the mRNAs encoding Histone H1 and Histone H3.3. This interaction requires all of the PIPPIN domains to work in concert as one functional protein. In addition, PIPPIN can be sumoylated in a thyroid hormone (T3)-dependent manner. This suggests that PIPPIN modification in response to extracellular stimuli may modulate the regulation of protein synthesis.

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