CPN2 抗体 (Alexa Fluor 555)
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- 抗原 See all CPN2 抗体
- CPN2 (Carboxypeptidase N Subunit 2 (CPN2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPN2 antibody is conjugated to Alexa Fluor 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CPN2
- 亚型
- IgG
- Top Product
- Discover our top product CPN2 Primary Antibody
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anti-Carboxypeptidase N Subunit 2 (CPN2) (C-Term) antibody
CPN2 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 2 (CPN2) (AA 74-103), (N-Term) antibodyCPN2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18703 unconjugated
anti-Carboxypeptidase N Subunit 2 (CPN2) (C-Term) antibodyCPN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 2 (CPN2) (AA 61-110) antibodyCPN2 适用: 人, 大鼠, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 2 (CPN2) (AA 249-540) antibodyCPN2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CPN2 (Carboxypeptidase N Subunit 2 (CPN2))
- 别名
- CPN2 (CPN2 产品)
- 别名
- cpn2 antibody, im:7138819 antibody, Cpn2 antibody, GB13055 antibody, DKFZp470I1612 antibody, ACBP antibody, 1300018K11Rik antibody, RGD1305170 antibody, carboxypeptidase N subunit 2 antibody, zgc:153913 antibody, carboxypeptidase N, polypeptide 2 antibody, CPN2 antibody, zgc:153913 antibody, Cpn2 antibody, CpipJ_CPIJ008561 antibody, CpipJ_CPIJ010495 antibody, CpipJ_CPIJ013628 antibody
- 背景
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Synonyms: CPN 2, CPN2, CPN-2, ACBP, Carboxypeptidase N 83 kDa chain, Carboxypeptidase N large subunit, Carboxypeptidase N regulatory subunit, Carboxypeptidase N subunit 2 [Precursor], carboxypeptidase N, polypeptide 2, CPN2_HUMAN.
Background: CPN2 is a zinc metalloprotease, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, kinins, and creatine kinase MM (CK-MM). By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding. It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma. It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1). CPN2, the 83 kDa subunit, binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit. CPN is a member of a larger family of carboxypeptidases, many of which also cleave arginine and lysine. Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, it has been difficult to elucidate the role of CPN in disease processes.
- 基因ID
- 1370
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