MYLK2 抗体 (Alexa Fluor 350)
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- 抗原 See all MYLK2 抗体
- MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYLK2 antibody is conjugated to Alexa Fluor 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MYLK2
- 亚型
- IgG
- Top Product
- Discover our top product MYLK2 Primary Antibody
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anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 330-548) antibody
MYLK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 161-260) antibodyMYLK2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) antibodyMYLK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 161-260) antibodyMYLK2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 1-596) antibodyMYLK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 1-596) antibodyMYLK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myosin Light Chain Kinase 2 (MYLK2) (AA 327-536) antibodyMYLK2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MYLK2 (Myosin Light Chain Kinase 2 (MYLK2))
- 别名
- MYLK2 (MYLK2 产品)
- 别名
- KMLC antibody, MLCK antibody, MLCK2 antibody, skMLCK antibody, 9830004H17Rik antibody, BB138278 antibody, Klmc antibody, Mlck antibody, myosin light chain kinase 2 antibody, myosin, light polypeptide kinase 2, skeletal muscle antibody, MYLK2 antibody, Mylk2 antibody, mylk2 antibody
- 背景
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Synonyms: KMLC, MLCK, MLCK2, MYLK 2, Myosin light chain kinase 2, Myosin light chain kinase 2 skeletal muscle, Myosin light chain kinase 2 skeletal/cardiac muscle, Skeletal muscle myosin light chain kinase, Skeletal myosin light chain kinase, skMLCK, MYLK2_HUMAN.
Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and myosin light chain kinases (MYLK, also designated MLCK). The MYLK kinases phosphorylate myosin regulatory light chains to catalyze myosin interaction with actin filaments resulting in contractile activity. Non-muscle, smooth muscle and skeletal/cardiac muscle MYLK isoforms exist. The MYLK gene (also designated MYLK1) encodes both smooth muscle and non-muscle isoforms as well as telokin, a small C-terminal isoform expressed only in smooth muscle with the capacity to stabilize unphosphorylated myosin filaments. Multiple transcript variants are described for the MYLK gene. Smooth-muscle and non-muscle MYLK isoforms are expressed in a wide variety of adult and fetal tissues. The skeletal/cardiac muscle isoforms of MYLK are encoded by a separate gene, MYLK2 (also designated skMLCK). MYLK appears to be a target for PAKs (p21-activated kinases). PAK1 interaction with MYLK results in a decrease in MYLK activity and myosin light chain phosphorylation.
- 基因ID
- 85366
- 途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation
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