TET2 抗体 (AA 1165-1215) (AbBy Fluor® 488)
Quick Overview for TET2 抗体 (AA 1165-1215) (AbBy Fluor® 488) (ABIN1402774)
抗原
See all TET2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1165-1215
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TET2
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亚型
- IgG
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anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibody
TET2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H8C7 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5H8B3 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyVerified TET2 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1-300) antibodyTET2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 21F11 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554), (N-Term) antibodyTET2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB37907 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554) antibodyTET2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C for 12 months.
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有效期
- 12 months
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- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
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别名
- TET2
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背景
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Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
Synonyms: MDS, KIAA1546, Methylcytosine dioxygenase TET2, TET2, Nbla00191 -
基因ID
- 54790
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UniProt
- Q6N021
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途径
- Warburg Effect
抗原
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