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LRSAM1 抗体 (Alexa Fluor 555)

LRSAM1 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN1402415
发货至: 中国
  • 抗原 See all LRSAM1 抗体
    LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
    适用
    人, 小鼠, 大鼠
    宿主
    • 38
    • 2
    克隆类型
    • 40
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRSAM1 antibody is conjugated to Alexa Fluor 555
    应用范围
    • 40
    • 17
    • 16
    • 12
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human LRSAM1
    亚型
    IgG
    Top Product
    Discover our top product LRSAM1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
    别名
    LRSAM1 (LRSAM1 产品)
    别名
    CMT2P antibody, RIFLE antibody, TAL antibody, leucine rich repeat and sterile alpha motif containing 1 antibody, LRSAM1 antibody, Lrsam1 antibody
    背景

    Synonyms: E3 ubiquitin protein ligase LRSAM1, hTAL, Leucine rich repeat and sterile alpha mot containing protein 1, RLE, TAL, Tsg101 associated ligase, LRSM1_HUMAN.

    Background: LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.

    基因ID
    90678
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