DPYSL2 抗体 (pSer518, pThr514) (Alexa Fluor 647)
-
- 抗原 See all DPYSL2 抗体
- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
-
抗原表位
- pSer518, pThr514
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DPYSL2 antibody is conjugated to Alexa Fluor 647
-
应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human CRMP2 around the phosphorylation site of Thr514+Ser518
- 亚型
- IgG
- Top Product
- Discover our top product DPYSL2 Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
- 别名
- CRMP2+ (DPYSL2 产品)
- 别名
- CRMP-2 antibody, CRMP2 antibody, DHPRP2 antibody, DRP-2 antibody, DRP2 antibody, N2A3 antibody, ULIP-2 antibody, ULIP2 antibody, TOAD-64 antibody, crmp2 antibody, dhprp2 antibody, drp-2 antibody, drp2 antibody, unc-33 antibody, unc33 antibody, dpysl2 antibody, CRMP 2 antibody, PCRMP 2 antibody, PCRMP-2 antibody, PCRMP2 antibody, PfCRMP 2 antibody, PfCRMP-2 antibody, AI851130 antibody, Crmp2 antibody, Musunc33 antibody, Ulip2 antibody, CRMP2A antibody, dihydropyrimidinase like 2 antibody, dihydropyrimidinase-like 2 antibody, dihydropyrimidinase like 2 L homeolog antibody, dihydropyrimidinase-like 2b antibody, cysteine repeat modular protein 2, putative antibody, DPYSL2 antibody, dpysl2.L antibody, dpysl2b antibody, PfCRMP2 antibody, dpysl2 antibody, Dpysl2 antibody
- 背景
-
Synonyms: CRMP2 phospho T514 + S518, CRMP2 phospho T514+S518, CRMP-2phospho Thr514+S518, p-CRMP2Thr514+S518, CRMP2/Dpysl2DRP 2, Collapsin response mediator protein 2, Collapsin response mediator protein hCRMP 2, CRAM, CRMP 2, DHPRP 2, DHPRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form,Dihydropyrimidinase related protein 2, DPYL 2, DPYL2, DPYSL 2, DPYSL2, DRP 2, DRP2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, Ulip2.
Background: Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.
- 基因ID
- 1808
- 途径
- Regulation of Cell Size
-