PDGF-AB Heterodimer (AA 81-180) 抗体 (Alexa Fluor 350)
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- 抗原
- PDGF-AB Heterodimer
- 抗原表位
- AA 81-180
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PDGFAA + PDGFBB
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDGF-AB Heterodimer
- 别名
- PDGFAA + PDGFBB
- 别名
- PDGF-A antibody, PDGF1 antibody, platelet derived growth factor subunit A antibody, PDGFA antibody
- 背景
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Synonyms: Becaplermin ,c sis ,c-sis ,FLJ12858 ,PDGF 1 ,PDGF 2 ,PDGF A ,PDGF A chain ,PDGF B ,PDGF B chain ,PDGF subunit B ,PDGF-2 ,Pdgfb ,PDGFB_HUMAN ,Platelet derived growth factor A chain precursor ,Platelet derived growth factor alpha polypeptide ,Platelet derived growth factor B chain precursor ,Platelet derived growth factor beta polypeptide simian sarcoma viral v-sis oncogene homolog ,Platelet derived growth factor beta polypeptide ,platelet-derived growth factor 2 ,Platelet-derived growth factor B chain ,Platelet-derived growth factor beta polypeptide ,Platelet-derived growth factor subunit B ,Platelet-derived growth factor, beta polypeptide oncogene SIS ,Proto-oncogene c-Sis ,SIS ,SSV ,v sis platelet derived growth factor beta polypeptide simian sarcoma viral oncogene homolog,
Background: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
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