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NPDC1 抗体 (AA 75-180) (Biotin)

NPDC1 适用: 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1394065
发货至: 中国
  • 抗原 See all NPDC1 抗体
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    抗原表位
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-180
    适用
    • 29
    • 21
    • 8
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 33
    • 1
    • 1
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPDC1 antibody is conjugated to Biotin
    应用范围
    • 26
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NPDC1
    亚型
    IgG
    Top Product
    Discover our top product NPDC1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    别名
    NPDC1 (NPDC1 产品)
    别名
    AI314472 antibody, NPDC-1 antibody, CAB antibody, CAB- antibody, CAB-1 antibody, CAB1 antibody, neural proliferation, differentiation and control, 1, gene 1 L homeolog antibody, neural proliferation, differentiation and control 1 antibody, neural proliferation, differentiation and control, 1 antibody, npdc1.1.L antibody, Npdc1 antibody, NPDC1 antibody
    背景

    Synonyms: AI314472, CAB1, Neural proliferation dferentiation and control protein 1, NPDC-1, NPDC1, NPDC1_HUMAN.

    Background: NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.

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