MPP5 抗体 (AA 201-300) (Biotin)
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- 抗原 See all MPP5 抗体
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
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抗原表位
- AA 201-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MPP5 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MPP5/PALS1
- 亚型
- IgG
- Top Product
- Discover our top product MPP5 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))
- 别名
- MPP5/PALS1 (MPP5 产品)
- 别名
- PALS1 antibody, 3830420B02Rik antibody, AI255216 antibody, AI644496 antibody, Pals1 antibody, mpp5 antibody, nok antibody, MAGUK p55 subfamily member 5 antibody, membrane palmitoylated protein 5 antibody, membrane protein, palmitoylated 5 L homeolog antibody, membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) antibody, membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5) antibody, Tsp_03061 antibody, MPP5 antibody, mpp5.L antibody, Mpp5 antibody, mpp5a antibody
- 背景
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Synonyms: FLJ12615, MAGUK p55 subfamily member 5, Membrane protein palmitoylated 5, MPP 5, MPP5, MPP5_HUMAN, PALS 1, PALS1, Protein associated with Lin-7, Stardust Drosophila, Stardust.
Background: Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
- 途径
- Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization
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