KALRN 抗体 (AA 1401-1500) (Alexa Fluor 488)
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- 抗原 See all KALRN 抗体
- KALRN (Kalirin, RhoGEF Kinase (KALRN))
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抗原表位
- AA 1401-1500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KALRN antibody is conjugated to Alexa Fluor 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KALRN/Duo
- 亚型
- IgG
- Top Product
- Discover our top product KALRN Primary Antibody
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anti-Kalirin, RhoGEF Kinase (KALRN) (C-Term) antibody
Verified KALRN 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (C-Term) antibodyKALRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (AA 2410-2661) antibodyKALRN 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (Internal Region) antibodyKALRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (Center) antibodyKALRN 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KALRN (Kalirin, RhoGEF Kinase (KALRN))
- 别名
- KALRN/Duo (KALRN 产品)
- 别名
- ARHGEF24 antibody, CHD5 antibody, CHDS5 antibody, DUET antibody, DUO antibody, HAPIP antibody, TRAD antibody, KALRN antibody, 2210407G14Rik antibody, AV235988 antibody, E530005C20Rik antibody, Gm539 antibody, Hapip antibody, Duo antibody, Kalirin antibody, kalirin RhoGEF kinase antibody, kalirin, RhoGEF kinase antibody, kalirin antibody, kalirin RhoGEF kinase L homeolog antibody, putative kalirin antibody, KALRN antibody, LOC460643 antibody, Kalrn antibody, kalrn antibody, kalrn.L antibody, LOC100473997 antibody, Smp_162970 antibody
- 背景
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Synonyms: Duo, FLJ16443, HAPIP, Huntingtin associated protein interacting protein duo , Huntingtin-associated protein-interacting protein, Kalirin isoform 2, Kalirin, KALRN , KALRN_HUMAN , Protein Duo, RhoGEF kinase, Serine/threonine kinase with Dbl and pleckstrin homology domains , Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, TRAD.
Background: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington?s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
- 途径
- Neurotrophin Signaling Pathway
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