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DACT3 抗体 (AA 575-629) (Alexa Fluor 350)

DACT3 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1393617
发货至: 中国
  • 抗原 See all DACT3 products
    DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))
    抗原表位
    • 14
    • 8
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 575-629
    适用
    • 36
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 36
    • 1
    克隆类型
    • 37
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DACT3 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 21
    • 17
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DACT3
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    DACT3 (Dapper, Antagonist of beta-Catenin, Homolog 3 (DACT3))
    别名
    DACT3 (DACT3 产品)
    别名
    EG666671 antibody, naa-3 antibody, DAPPER3 antibody, RRR1 antibody, RGD1563892 antibody, dishevelled binding antagonist of beta catenin 3 antibody, dishevelled-binding antagonist of beta-catenin 3 antibody, DACT3 antibody, Dact3 antibody
    背景

    Synonyms: Antagonist of beta-catenin Dapper homolog 3, Arginine rich region 1, Arginine rich region 1 protein, Arginine-rich region 1 protein, Dact3 antibody, DACT3_HUMAN, Dapper antagonist of beta catenin 3, Dapper antagonist of beta catenin homolog 3 Xenopus laevis, Dapper homolog 3, Dapper3, Dpr3 antibodyRRR1, RRR1, Thymus expressed gene 3 like.

    Background: Dapper3 is a 629 amino acid protein and mammalian homolog of the Xenopus laevis protein dapper. As a member of the dapper family, Dapper3 plays a role in postnatal brain development and contains a C-terminal PDZ-binding motif that facilitates interaction with the PDZ domains of DSH (Dishevelled) family proteins. As the predominant dapper family member found in adult brain, Dapper 3 localizes to hippocampus, Purkinje cell layer and every layer of the dorsal forebrain and cerebral cortex and is also found in the developing murine central nervous system. Dapper3 is also expressed in uterus, ventral somites, branchial arch mesenchyme, aortic sac, aortic arches, limb bud mesenchyme and craniofacical mesenchyme. Mapping to human chromosome 19q13.32, Dapper3 has been identified as a negative regulator of Wnt/beta-catenin signaling in colorectal cancer.

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