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EN1 抗体 (AA 351-392) (Alexa Fluor 647)

EN1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN1393068
发货至: 中国
  • 抗原 See all EN1 抗体
    EN1 (Engrailed Homeobox 1 (EN1))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 351-392
    适用
    • 24
    • 20
    • 18
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 1
    克隆类型
    • 28
    • 2
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EN1 antibody is conjugated to Alexa Fluor 647
    应用范围
    • 25
    • 13
    • 12
    • 12
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EN1/Engrailed 1
    亚型
    IgG
    Top Product
    Discover our top product EN1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EN1 (Engrailed Homeobox 1 (EN1))
    别名
    EN1/Engrailed 1 (EN1 产品)
    别名
    EN1 antibody, En-1 antibody, Mo-en.1 antibody, ENG-1 antibody, en-1 antibody, en1 antibody, eng1 antibody, zgc:100771 antibody, en1-A antibody, engrailed-1 antibody, xen1 antibody, Gg-En-1 antibody, en-3 antibody, engrailed antibody, engrailed homeobox 1 antibody, engrailed 1 antibody, engrailed homeobox 1a antibody, engrailed homeobox 1 S homeolog antibody, EN1 antibody, En1 antibody, en1a antibody, en1.S antibody
    背景

    Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.

    Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.

    基因ID
    2019
    UniProt
    Q05925
    途径
    Dopaminergic Neurogenesis
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