APBA2 抗体 (AA 351-450) (Alexa Fluor 488)
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- 抗原 See all APBA2 抗体
- APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))
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抗原表位
- AA 351-450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APBA2 antibody is conjugated to Alexa Fluor 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Sheep,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human APBA2
- 亚型
- IgG
- Top Product
- Discover our top product APBA2 Primary Antibody
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anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) (AA 15-158) antibody
APBA2 适用: 人 ELISA, WB, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7G5G11 unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) (Internal Region) antibodyAPBA2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) (AA 459-722) antibodyAPBA2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))
- 别名
- APBA2 (APBA2 产品)
- 别名
- MGC83599 antibody, D15S1518E antibody, HsT16821 antibody, LIN-10 antibody, MGC:14091 antibody, MINT2 antibody, X11-BETA antibody, X11L antibody, X11-like antibody, XllL antibody, mXllL antibody, Mint2 antibody, amyloid beta precursor protein binding family A member 2 antibody, amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog antibody, amyloid beta (A4) precursor protein-binding, family A, member 2 antibody, APBA2 antibody, apba2.L antibody, Apba2 antibody
- 背景
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Synonyms: Adapter protein X11beta, Amyloid beta A4 precursor protein-binding family A member 2, APBA2, APBA2_HUMAN, D15S1518E, HsT16821, LIN 10, Mint 2, Mint-2, Neuron-specic X11L protein, Neuronal Munc18-1-interacting protein 2, Phosphotyrosine binding/interacting domain PTB bearing protein, X11 beta, X11l.
Background: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer?s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11 Alpha (also designated Mint 1), X11 Beta (Mint 2) and X11 Gamma(Mint 3).
- 途径
- Synaptic Vesicle Exocytosis
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