GNRHR2 抗体 (AA 81-180) (Alexa Fluor 488)
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- 抗原 See all GNRHR2 products
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
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抗原表位
- AA 81-180
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适用
- Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNRHR2 antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- Pig
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GNRHR2
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
- 别名
- GNRHR2 (GNRHR2 产品)
- 别名
- gnrhr1/iii antibody, GnRH-II-R antibody, gonadotropin releasing hormone receptor 2 (pseudogene) antibody, gonadotropin-releasing hormone (type 2) receptor 2 antibody, gnrhr2 antibody, GNRHR2 antibody
- 背景
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Synonyms: GnRH IIR, Putative gonadotropin-releasing hormone II receptor, gonadotropin-releasing hormone type 2 receptor 2, GnRH-II-R, Type II GnRH receptor, GNRR2_HUMAN.
Background: Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
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