Complexin 1 抗体 (AA 31-100) (Alexa Fluor 350)
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- 抗原 See all Complexin 1 (CPLX1) 抗体
- Complexin 1 (CPLX1)
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抗原表位
- AA 31-100
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Complexin 1 antibody is conjugated to Alexa Fluor 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Cow,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CPLX1
- 亚型
- IgG
- Top Product
- Discover our top product CPLX1 Primary Antibody
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anti-Complexin 1 (CPLX1) (AA 31-100) antibody
CPLX1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibodyCPLX1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (N-Term) antibodyCPLX1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibodyCPLX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complexin 1 (CPLX1) (AA 33-60) antibodyCPLX1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23961 unconjugated
anti-Complexin 1 (CPLX1) (AA 1-134) antibody (PE)CPLX1 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal PE
anti-Complexin 1 (CPLX1) (AA 1-134) antibody (APC)CPLX1 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal APC
anti-Complexin 1 (CPLX1) (AA 39-69), (Middle Region) antibodyCPLX1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Complexin 1 (CPLX1)
- 别名
- CPLX1 (CPLX1 产品)
- 别名
- MGC84299 antibody, CPLX1 antibody, CPX-I antibody, CPX1 antibody, 921-S antibody, complexin 1 L homeolog antibody, complexin 1 antibody, cplx1.L antibody, CPLX1 antibody, cplx1 antibody, Cplx1 antibody
- 背景
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Synonyms: complexin 1, Complexin I, Complexin-1, CPLX1, CPLX1_HUMAN, CPX I, CPX-I, CPX1, Synaphin 2, Synaphin-2, 921-S.
Background: Complexin 1 and Complexin 2, also designated Synaphin 1 and Synaphin 2, contain an a-helical middle domain of approximately 58 amino acids. Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, respectively, and in cytoplasmic pools during early stages of development. Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain. Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediately after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion. Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation. A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, an autosomal dominant neurodegenerative disorder. Changes in the neurotransmitter release might contribute to the motor, emotional and cognitive dysfunctions seen in these mice.
- 途径
- Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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