LEFTY1 抗体 (AA 51-150) (Alexa Fluor 555)
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- 抗原 See all LEFTY1 抗体
- LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))
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抗原表位
- AA 51-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LEFTY1 antibody is conjugated to Alexa Fluor 555
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Lefty
- 亚型
- IgG
- Top Product
- Discover our top product LEFTY1 Primary Antibody
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anti-Left-Right Determination Factor 1 (LEFTY1) (AA 78-361) antibody
LEFTY1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 1-366) antibodyLEFTY1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 291-320) antibodyLEFTY1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (Internal Region) antibodyLEFTY1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (N-Term) antibodyLEFTY1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 1-366) antibodyLEFTY1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 43-364) antibodyLEFTY1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 169-368) antibodyLEFTY1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 223-260) antibodyLEFTY1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Left-Right Determination Factor 1 (LEFTY1) (AA 1-366) antibodyLEFTY1 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4D7 unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))
- 别名
- Lefty (LEFTY1 产品)
- 别名
- atv antibody, cb73 antibody, antivin antibody, ik:tdsubc_2b12 antibody, xx:tdsubc_2b12 antibody, LEFTY1 antibody, AI450052 antibody, Ebaf antibody, Leftb antibody, Stra3 antibody, Tgfb4 antibody, lefty antibody, lefty-1 antibody, RGD1561867 antibody, LEFTB antibody, LEFTYB antibody, lefty1 antibody, signaling molecule lefty1 antibody, left-right determination factor 1 antibody, left right determination factor 1 antibody, lft1 antibody, lefty1 antibody, LOC699924 antibody, LEFTY1 antibody, LOC100408003 antibody, LOC100597378 antibody, Lefty1 antibody
- 背景
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Synonyms: Protein lefty-1, AI450052, Ebaf, Left right determination factor 1, left right determination factor, Left right determination factor B, left-right determination factor, LEFT-RIGHT DETERMINATION FACTOR 1, LEFTY1, left-right determination, factor B, LEFT-RIGHT DETERMINATION, FACTOR B, LEFTY B, LEFTB, LEFTY 1, Lefty, lefty-1, LEFTY1, LEFTY1, MOUSE, HOMOLOG OF antibody, LEFTYB, Protein lefty-B, RGD1561867, Stimulated by retinoic acid gene 3 protein, STRA3, TGF beta 4, TGF-beta-4, Tgfb4, Transforming growth factor beta 4, Transforming growth factor beta-4.
Background: During vertebrate embryogenesis, a left right axis is established. Secreted growth factors of the TGF beta family, including gene products derived from nodal, lefty 1 and lefty 2, play crucial roles in establishing left right asymmetries. TGF beta (Transforming growth factor beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells. TGF beta actions are directed by ligand induced activation of TGF beta receptors. Complexes formed move into the nucleus, where they act as components of a transcriptional complex. Lefty, a novel member of the TGF beta superfamily, inhibits TGF beta signaling. Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF beta receptor. Lefty also inhibits events downstream from R Smad phosphorylation. Lefty provides a repressed state of TGF beta responsive genes. The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, and Lefty A and Lefty B in humans. Members of the TGF beta superfamily require processing for their activation. Cleavage is therefore an essential step for Lefty activation. Lefty is synthesized as a large inactive precursor (41 Kda) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms). The 28 kDa form induces MAPK activity.
- 基因ID
- 10637
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