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Proteoglycan 4 抗体 (AA 1151-1250) (Alexa Fluor 350)

PRG4 适用: 小鼠, 大鼠, 兔 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1389717
发货至: 中国
  • 抗原 See all Proteoglycan 4 (PRG4) 抗体
    Proteoglycan 4 (PRG4)
    抗原表位
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1151-1250
    适用
    • 18
    • 18
    • 17
    • 14
    小鼠, 大鼠, 兔
    宿主
    • 28
    • 2
    • 1
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Proteoglycan 4 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 26
    • 14
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 兔, 大鼠
    预测反应
    Human,Dog,Cow
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Lubricin/SZP
    亚型
    IgG
    Top Product
    Discover our top product PRG4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Proteoglycan 4 (PRG4)
    别名
    Lubricin/SZP (PRG4 产品)
    别名
    CACP antibody, HAPO antibody, JCAP antibody, MSF antibody, SZP antibody, bG174L6.2 antibody, lubricin antibody, prg4 antibody, si:dkey-97o5.3 antibody, zgc:122988 antibody, PRG4 antibody, DOL54 antibody, proteoglycan 4 antibody, proteoglycan 4b antibody, proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) antibody, PRG4 antibody, Prg4 antibody, prg4b antibody
    背景

    Synonyms: Superficial zone proteoglycan, articular superficial zone protein, bG174L6.2, CACP, camptodactyly arthropathy coxa vara pericarditis syndrome gene, FLJ32635, HAPO, Jacobs camptodactyly-arthropathy-pericarditis syndrome gene, JCAP, megakaryocyte stimulating factor, MSF, PRG 4, PRG4, proteoglycan 4, Proteoglycan4, Superficial zone proteoglycan, SZP.

    Background: Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.

    基因ID
    10216
    UniProt
    Q92954
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