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CACNA1S 抗体 (AA 951-1001)

CACNA1S 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387901
发货至: 中国
  • 抗原 See all CACNA1S 抗体
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 951-1001
    适用
    人, 小鼠, 大鼠
    宿主
    • 22
    • 2
    克隆类型
    • 23
    • 1
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA1S antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CACNA1S
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

  • 抗原
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    别名
    CACNA1S (CACNA1S 产品)
    别名
    CACNA1S antibody, cav1.1 antibody, ca(v)1.1 antibody, CACNL1A3 antibody, CCHL1A3 antibody, Cav1.1 antibody, HOKPP antibody, HOKPP1 antibody, MHS5 antibody, TTPP1 antibody, hypoPP antibody, AW493108 antibody, Cchl1a3 antibody, fmd antibody, mdg antibody, sj antibody, caV1.1 antibody, calcium voltage-gated channel subunit alpha1 S antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit antibody, CACNA1S antibody, cacna1s.S antibody, Cacna1s antibody
    背景

    Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3

    Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

    基因ID
    779
    UniProt
    Q13698
    途径
    Skeletal Muscle Fiber Development
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