CELSR3 抗体 (AA 1601-1700)
-
- 抗原 See all CELSR3 抗体
- CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))
-
抗原表位
- AA 1601-1700
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CELSR3 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Flamingo homolog 1
- 亚型
- IgG
- Top Product
- Discover our top product CELSR3 Primary Antibody
-
-
- 应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).
: "
-
Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." in: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).
-
- 抗原
- CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))
- 别名
- CELSR3/Flamingo homolog 1 (CELSR3 产品)
- 别名
- CDHF11 antibody, EGFL1 antibody, FMI1 antibody, HFMI1 antibody, MEGF2 antibody, RESDA1 antibody, Megf2 antibody, Fmi1 antibody, flamingo antibody, mKIAA0812 antibody, cadherin EGF LAG seven-pass G-type receptor 3 antibody, cadherin, EGF LAG seven-pass G-type receptor 3 antibody, CELSR3 antibody, Celsr3 antibody
- 背景
-
Synonyms: Cadherin EGF LAG seven-pass G-type receptor 3, Cadherin family member 11, CDHF11, CELR3_HUMAN, CELSR3, EGF-like protein 1, EGFL1, Epidermal growth factor-like protein 1, Flamingo, Flamingo homolog 1, FMI1, HFMI1, MEGF2, Multiple EGF-like domains protein 2, Multiple epidermal growth factor-like domains protein 2.
Background: Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.
- 基因ID
- 1951
- UniProt
- Q9NYQ7
-