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APBB2 抗体 (AA 251-350)

APBB2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387523
发货至: 中国
  • 抗原 See all APBB2 抗体
    APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
    抗原表位
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    适用
    • 38
    • 17
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 2
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APBB2 antibody is un-conjugated
    应用范围
    • 31
    • 12
    • 12
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human APBB2
    亚型
    IgG
    Top Product
    Discover our top product APBB2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
    别名
    APBB2/FE65L1 (APBB2 产品)
    别名
    FE65L antibody, FE65L1 antibody, 2310007D03Rik antibody, Rirl1 antibody, TR2L antibody, Zfra antibody, RGD1562438 antibody, APBB2 antibody, fe65l antibody, fe65l1 antibody, DKFZp469I236 antibody, si:ch211-201g8.2 antibody, amyloid beta precursor protein binding family B member 2 antibody, amyloid beta (A4) precursor protein-binding, family B, member 2 antibody, amyloid beta (A4) precursor protein-binding, family B, member 2b antibody, APBB2 antibody, Apbb2 antibody, apbb2 antibody, apbb2b antibody
    背景

    Synonyms: Amyloid beta A4 precursor protein-binding, family B, member 2 Fe65 like, Amyloid beta A4 precursor protein binding family B member 2, Amyloid beta A4 precursor protein-binding family B member 2, APBB 2, APBB2, APBB2_HUMAN, Fe65 like 1, Fe65 like, Fe65 like protein, FE65L 1, FE65L, FE65L1, Protein Fe65-like 1, Rirl 1, Rirl1, TR2 L, TR2L, Zfra, Zinc finger like protein.

    Background: Fe65L is a 758 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the -Amyloid precursor protein, Fe65L is thought to modulate the internalization and, therefore, the accessibility and function of -Amyloid. Via its ability to control the intracellular accumulation of -Amyloid, Fe65L is thought to play a role in the pathogenesis of Alzheimer's disease. Multiple isoforms of Fe65L exist due to alternative splicing events. The gene encoding Fe65L maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

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