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FAS 抗体 (AA 81-170)

FAS 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387305
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    抗原表位
    • 25
    • 16
    • 15
    • 8
    • 8
    • 6
    • 5
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    • 4
    • 4
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    • 3
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    AA 81-170
    适用
    • 209
    • 66
    • 61
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 157
    • 86
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 155
    • 96
    • 1
    多克隆
    标记
    • 119
    • 27
    • 25
    • 12
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This FAS antibody is un-conjugated
    应用范围
    • 162
    • 114
    • 71
    • 64
    • 35
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    • 30
    • 26
    • 26
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    • 18
    • 9
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    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FAS/Apo-1
    亚型
    IgG
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).

  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    Apo-1 (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景

    Synonyms: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, FAS

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    基因ID
    355
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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