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FAS 抗体 (AA 81-170)

This anti-FAS antibody is a 兔 多克隆 antibody detecting FAS in WB, FACS 和 ELISA. Suitable for 人, 大鼠 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1387305
发货至: 中国

Quick Overview for FAS 抗体 (AA 81-170) (ABIN1387305)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

  • 248
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  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 183
  • 120
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1

克隆类型

  • 179
  • 130
  • 1
多克隆

标记

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  • 13
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  • 1
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This FAS antibody is un-conjugated

应用范围

  • 187
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  • 39
  • 32
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  • 21
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  • 1
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Western Blotting (WB), Flow Cytometry (FACS), ELISA
  • 抗原表位

    • 24
    • 23
    • 16
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-170

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FAS/Apo-1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).

  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    Apo-1

    背景

    Synonyms: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, FAS

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    基因ID

    355

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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