SHANK3 抗体 (AA 1151-1250)
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- 抗原 See all SHANK3 抗体
- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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抗原表位
- AA 1151-1250
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SHANK3 antibody is un-conjugated
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应用范围
- Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SHANK3
- 亚型
- IgG
- Top Product
- Discover our top product SHANK3 Primary Antibody
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anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (HRP)
SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (FITC)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Biotin)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PE)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 PE
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (APC)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 APC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PerCP)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 488)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 594)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 390)SHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 Atto 390
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibodySHANK3 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S69 unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
- 别名
- SHANK3 (SHANK3 产品)
- 别名
- DEL22q13.3 antibody, PROSAP2 antibody, PSAP2 antibody, SCZD15 antibody, SPANK-2 antibody, Prosap2 antibody, AI841104 antibody, Shank3b antibody, SH3 and multiple ankyrin repeat domains 3 antibody, SH3 and multiple ankyrin repeat domains protein 3 antibody, SHANK3 antibody, shank3 antibody, Shank3 antibody
- 背景
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Synonyms: PSAP2, SCZD15, PROSAP2, SPANK-2, DEL22q13.3, SH3 and multiple ankyrin repeat domains protein 3, Shank3, Proline-rich synapse-associated protein 2, KIAA1650
Background: Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
- 基因ID
- 85358
- UniProt
- Q9BYB0
- 途径
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
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