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MPDZ 抗体 (AA 388-480)

MPDZ 适用: 人 FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386679
发货至: 中国
  • 抗原 See all MPDZ 抗体
    MPDZ (Multiple PDZ Domain Protein (MPDZ))
    抗原表位
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 388-480
    适用
    • 23
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MPDZ antibody is un-conjugated
    应用范围
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MUPP1/MPDZ
    亚型
    IgG
    Top Product
    Discover our top product MPDZ Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MPDZ (Multiple PDZ Domain Protein (MPDZ))
    别名
    MUPP1/MPDZ (MPDZ 产品)
    别名
    HYC2 antibody, MUPP1 antibody, AI225843 antibody, B930003D11Rik antibody, multiple PDZ domain crumbs cell polarity complex component antibody, multiple PDZ domain protein antibody, Multiple PDZ domain protein antibody, inactivation-no-after-potential D protein antibody, multiple pdz domain protein, putative antibody, MPDZ antibody, Mpdz antibody, mpz-1 antibody, LOC5569990 antibody, Smp_168960 antibody
    背景

    Synonyms: MPDZ, Multi PDZ domain protein 1, Multi-PDZ domain protein 1, multiple PDZ domain protein, MPDZ_HUMAN.

    Background: MPDZ is a 2,042 amino acid peripheral membrane protein that colocalizes with SR-2C on the apical membrane of epithelial choroid plexus cells. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas, MPDZ causes clustering of SR-2C, a serotonin receptor, at the cell surface. MPDZ is member of the NMDAR signaling complex that is involved in regulating AMPAR potentiation and synaptic plasticity in excitatory synapses. As a tight junction protein in epithelial cells, MPDZ interacts with SSTR3, a G-protein-coupled receptor, to regulate transepithelial permeability in a pertussis toxin sensitive manner. MPDZ, along with Kir4.2, may form a complex with other proteins in the nephron and regulate ion transport. MPDZ contains one L27 domain and thirteen PDZ domains.

    途径
    Synaptic Membrane, Phototransduction
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