ATM 抗体 (pTyr170)
Quick Overview for ATM 抗体 (pTyr170) (ABIN1386564)
抗原
See all ATM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr170
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human ATM around the phosphorylation site of Tyr170 [SV(p-Y)FR]
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亚型
- IgG
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anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM 适用: 人 WB, IHC, ELISA, IF, IP, FACS, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM 适用: 人 WB, IHC, ELISA, IF, IP, FACS, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibodyATM 适用: 人, 小鼠 WB, IHC, ELISA, IF, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibodyATM 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibodyATM 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 4E11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7C10D8 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody (HRP)ATM 适用: 人 WB, IHC, ELISA, FM 宿主: 小鼠 Monoclonal 10H11-E12 HRP
anti-Ataxia Telangiectasia Mutated (ATM) (AA 486-742) antibodyATM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM 适用: 人 IHC, ELISA, FACS 宿主: 兔 Monoclonal 3G11 unconjugated Recombinant Antibody
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应用备注
- IHC-P (1:100-500),IF (p) (1:100-500)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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别名
- ATM
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背景
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Synonyms: ATM Tyr170, ATM Y170, p-ATM Tyr170, p-ATM Y170, A-T mutated, A-T mutated homolog, AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated, AT protein, AT1, ATA, Ataxia telangiectasia gene mutated in human beings, Ataxia telangiectasia mutated, Ataxia telangiectasia mutated gene, Ataxia telangiectasia mutated homolog human, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, ATM, ATM_HUMAN, DKFZp781A0353, Human phosphatidylinositol 3 kinase homolog, MGC74674, Serine protein kinase ATM, Serine-protein kinase ATM, Serine/threonine-protein kinase ATM, T cell prolymphocytic leukemia, Tefu, TEL1, TEL1, telomere maintenance 1, homolog, TELO1, Telomere fusion protein, TPLL.
Background: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
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分子量
- 370kDa
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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